abstract：:B cells in patients with rheumatoid arthritis (RA) are hyperactivated. Although B cell receptor signal transduction may be affected by various response regulators, CD22 plays an important role as a response regulator of B cells. Therefore, we investigated and examined CD22 expression on peripheral blood B cells of pat...

journal_title：Clinical rheumatology

authors： Nakiri Y,Minowa K,Suzuki J,Mitsuo A,Amano H,Morimoto S,Tokano Y,Takasaki Y

更新日期：2007-10-01 00:00:00

abstract：:Antibodies to beta(2)-glycoprotein I (anti-beta(2)-GPI) have been reported to have stronger association with clinical antiphospholipid syndrome (APS) than anticardiolipin antibodies (aCL) and lupus anticoagulant (LAC). We investigated the sensitivity and specificity of ELISA for anti-beta(2)-GPI in Thai systemic lupus...

journal_title：Clinical rheumatology

authors： Parkpian V,Verasertniyom O,Vanichapuntu M,Totemchokchyakarn K,Nantiruj K,Pisitkul P,Angchaisuksiri P,Archararit N,Rachakom B,Ayurachai K,Janwityanujit S

更新日期：2007-10-01 00:00:00

abstract：:Behçet's disease (BD) has well-defined pulmonary complications, but cardiopulmonary exercise testing and the strength of the respiratory muscles have not been studied in detail. We aimed to investigate the pulmonary functions tests, inspiratory and expiratory muscle strength and endurance, cardiopulmonary exercise tes...

journal_title：Clinical rheumatology

authors： Gökoğlu F,Yorgancioğlu ZR,Ustün N,Ardiç FA

更新日期：2007-09-01 00:00:00

abstract：:Sjõgren's disease is one of the most common rheumatological diseases and can present with a variety of extra-glandular manifestations. Lymphocytic Interstitial Pneumonitis (LIP) is the most common lung pathology in these patients. It is important to know and recognize this condition because it is potentially treatable...

journal_title：Clinical rheumatology

authors： Dalvi V,Gonzalez EB,Lovett L

更新日期：2007-08-01 00:00:00

abstract：:We present a patient with previously diagnosed hypocomplementemic urticarial vasculitis syndrome, with skin, lung, and renal involvement, who presented with congestive cardiac failure. During the course of her hospitalization, she was also found to have profound proximal muscle weakness in both upper and lower limbs a...

journal_title：Clinical rheumatology

authors： Chew GY,Gatenby PA

更新日期：2007-08-01 00:00:00

abstract：:Cardiovascular disease is a major health care problem and the most common cause of death among individuals from developed nations. Our understanding of atherosclerosis has evolved from a passive process resulting in narrowing of the lumen and consequent myocardial ischemia to a dynamic process that involves inflammati...

journal_title：Clinical rheumatology

authors： Chung CP,Avalos I,Raggi P,Stein CM

更新日期：2007-08-01 00:00:00

abstract：:One of the most important therapeutic goal in hyperhidrosis treatment is to seek for the underlying cause and to tailor the treatment accordingly. A detailed history and prompt physical examination are needed to clarify the etiological factor. In this study, we report a 34-year-old woman with a diagnosis of thoracic o...

journal_title：Clinical rheumatology

authors： Ozdemir O,Ozçakar L

更新日期：2007-08-01 00:00:00

abstract：:Visceral leishmaniasis (VL) is a severe disease that can develop in immunocompromised patients. Antitumor necrosis factor-alpha (TNF-alpha) treatment of rheumatoid arthritis can result in clinical benefits, but with an increased risk of opportunistic infections. Leishmania infection in patients treated with TNF-alpha ...

journal_title：Clinical rheumatology

authors： Bagalas V,Kioumis I,Argyropoulou P,Patakas D

更新日期：2007-08-01 00:00:00

abstract：:A case of pseudo-pseudohypoparathyroidism (PPH) with shortening of the left femur and tibia and coalition of the base of the fourth metacarpals with capitatum and hamatum in bilateral wrist joints was presented. Involvement of the fourth digits both in hands and feet were more prominent on the left side, with shorteni...

journal_title：Clinical rheumatology

authors： Unlu Z,Orguc S,Yilmaz Ovali G,Bayindir P

更新日期：2007-07-01 00:00:00

abstract：:We describe two cases of rheumatoid arthritis (RA) patients and concomitant hepatitis C virus infection (HCV), treated with cyclosporine A (CsA) and anti-TNF-alpha agents. SGOT/SGPT and HCV-RNA serum levels remained unchanged longer than 1 year of treatment. No side effects were registered. We suggest that combination...

journal_title：Clinical rheumatology

authors： Bellisai F,Giannitti C,Donvito A,Galeazzi M

更新日期：2007-07-01 00:00:00

abstract：:The aims of this study were to characterize a minimally invasive technique of minor salivary gland biopsy of the lower lip and to present a large patient material undergoing this procedure because of a suspicion of Sjögren's syndrome (SS), as well as to assess the procedure's short-term and long-term value as a diagno...

journal_title：Clinical rheumatology

authors： Teppo H,Revonta M

更新日期：2007-07-01 00:00:00

abstract：:Musculoskeletal disorders represent a large and growing clinical challenge to primary care clinicians. Unfortunately, there appears to be a gap in current training and continuing education to meet this challenge. We used script concordance within a continuing medical education program entitled "Joint Adventures" to as...

journal_title：Clinical rheumatology

authors： Petrella RJ,Davis P

更新日期：2007-07-01 00:00:00

abstract：:The objective of the study was to analyze the prognostic factors of radiographic progression in a series of patients with early rheumatoid arthritis (RA) after 2 years of therapy with a structured algorithm using disease-modifying antirheumatic drugs (DMARDs) and very low doses of oral glucocorticoids. One hundred and...

journal_title：Clinical rheumatology

authors： Sanmartí R,Gómez-Centeno A,Ercilla G,Larrosa M,Viñas O,Vazquez I,Gómez-Puerta JA,Gratacós J,Salvador G,Cañete JD

更新日期：2007-07-01 00:00:00

abstract：:Polymyositis may occur along with other manifestations of chronic graft vs host disease after allogeneic bone marrow transplantation (BMT). Donor lymphocyte infusion (DLI) could produce durable remissions in relapsed patients with chronic myelogenous leukemia (CML) but it may contribute to the development of polymyosi...

journal_title：Clinical rheumatology

authors： Liu FC,Chen CH,Chao TY

更新日期：2007-07-01 00:00:00

abstract：:A 67-year-old woman, suffering from continuous hemoptysis, was admitted to our hospital where she was managed with mechanical ventilation. Computed tomography of the chest demonstrated bilateral massive alveolar hemorrhage without evidence of infectious disease. She was diagnosed with anti-myeloperoxidase antineutroph...

journal_title：Clinical rheumatology

authors： Kawasaki S,Nakamura H,Honda E,Iwanaga N,Kawakami A,Ida H,Origuchi T,Honda S,Tsuchihashi Y,Yoshimine H,Eguchi K

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVE:To test the efficacy of Infliximab, a chimeric monoclonal antibody against TNF-alpha, in the treatment of Takayasu arteritis. MATERIALS AND METHODS:We used infliximab at an initial dose of 3 mg/kg i.v. at weeks 0, 2, 6, and 8 thereafter in combination with methotrexate or azathioprine, to treat four patients...

journal_title：Clinical rheumatology

authors： Karageorgaki ZT,Mavragani CP,Papathanasiou MA,Skopouli FN

更新日期：2007-06-01 00:00:00

abstract：:Gastrointestinal tract (GIT) is the most common organ system involved in systemic sclerosis (SSc). GIT involvement is mainly attributed to GIT dismobility and wide mouth diverticular. GIT involvement in SSc can be also severely debilitating and even life threatening. To our knowledge, the presence of gastrointestinal ...

journal_title：Clinical rheumatology

authors： Plastiras SC,Tzivras M,Vlachoyiannopoulos PG

更新日期：2007-06-01 00:00:00

abstract：:Behçet's disease (BD) related amyloidosis is relatively rare. Serum amyloid A protein (SAA) protein gene polymorphism is one of the factors implicated in the pathogenesis of AA type amyloidosis. The aim of this study is to investigate SAA1 gene polymorphism in different patient groups: (1) BD related amyloidosis, (2) ...

journal_title：Clinical rheumatology

authors： Utku U,Dilek M,Akpolat I,Bedir A,Akpolat T

更新日期：2007-06-01 00:00:00

abstract：:It is commonly believed that infliximab-induced anticardiolipin antibody belongs to the IgM subclass but not the IgG subclass and that the IgM subclass could not produce clinical symptoms. However, we had a patient with scleroderma overlap/rheumatoid arthritis who developed thrombocytopenia associated with the appeara...

journal_title：Clinical rheumatology

authors： Hamaguchi M,Kawahito Y,Ishino H,Yoshida M,Yoshikawa T

更新日期：2007-06-01 00:00:00

abstract：:Behçet's disease is a systemic vasculitic syndrome with unknown etiology. The aim of the present study was to compare the Helicobacter pylori seropositivity and cytotoxin associated gene-A status in patients with Behçet's disease. Ninety-one patients with Behçet's disease and 83 age- and sex-matched persons with or wi...

journal_title：Clinical rheumatology

authors： Apan TZ,Gürsel R,Dolgun A

更新日期：2007-06-01 00:00:00

abstract：:CD30/CD30L and CD40/CD40L are molecules from the tumor necrosis factor (TNF) superfamily. They have a major effect on communications between the B and T cells, which leads to control of maturation, proliferation, and apoptosis of those cells. The aim of this study was to compare the levels of a soluble form of CD30 (s...

journal_title：Clinical rheumatology

authors： Ciferská H,Horák P,Hermanová Z,Ordeltová M,Zadrazil J,Tichý T,Scudla V

更新日期：2007-05-01 00:00:00

abstract：:In addition to the debilitating fatigue, the majority of patients with chronic fatigue syndrome (CFS) experience chronic widespread pain. These pain complaints show the greatest overlap between CFS and fibromyalgia (FM). Although the literature provides evidence for central sensitization as cause for the musculoskelet...

journal_title：Clinical rheumatology

authors： Meeus M,Nijs J

更新日期：2007-04-01 00:00:00

abstract：:Calcinosis, Raynaud's phenomenon, oesophageal dysmotility, sclerodactyly, telangiectasia (CREST) syndrome, a limited form of systemic sclerosis, is sometimes complicated by primary biliary cirrhosis (PBC). A 52- and 61-year-old Japanese woman with PBC-CREST overlap syndrome accompanied by Sjögren's syndrome, and Hashi...

journal_title：Clinical rheumatology

authors： Nakamura T,Higashi S,Tomoda K,Tsukano M,Sugi K

更新日期：2007-04-01 00:00:00

abstract：:Very recently, several studies have convincingly demonstrated the role of infection in the development of the antiphospholipid syndrome. Cross antibody-mediated reactivity due to molecular mimicry between endothelial glycoproteins and microbial products was considered as an important pathogenic mechanism. However, ano...

journal_title：Clinical rheumatology

authors： Rozin AP

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVES:Action potential simulation (APS) is becoming a popular method of pain reduction. Nevertheless, little is known about the efficacy of this relatively new treatment. The aim of this study was to investigate whether APS helps to reduce pain, improves patients' perception of daily functioning and social partici...

journal_title：Clinical rheumatology

authors： Fengler RK,Jacobs JW,Bac M,van Wijck AJ,van Meeteren NL

更新日期：2007-03-01 00:00:00

abstract：:A 73-year-old woman was admitted to our hospital because of persistent high fever and cough, generalized myalgia, and renal dysfunction. Laboratory examination revealed severe inflammatory signs, pulmonary fibrosis, progression of renal impairment with active nephritic urinary sediments, and a high titer of myeloperox...

journal_title：Clinical rheumatology

authors： Sugimoto T,Kanasaki K,Koyama T,Yokomaku Y,Yasuda H,Kashiwagi A,Koya D

更新日期：2007-03-01 00:00:00

abstract：:Lysosomal storage diseases are rare metabolic disorders, some of which can now be treated using enzyme replacement therapies. Because the time point of treatment initiation significantly influences the outcome in Gaucher disease, Fabry disease, and mucopolysaccharidosis type I, early diagnosis is of utmost importance....

journal_title：Clinical rheumatology

authors： Manger B,Mengel E,Schaefer RM

更新日期：2007-03-01 00:00:00

abstract：:There are few reports about the coexistence of Sjögren's syndrome (SS) and ankylosing spondylitis (AS). To evaluate the frequency of SS in patients with AS. We studied 70 patients with AS presenting to the university outpatient clinic between January 2002 and November 2003. All the patients were asked about sicca symp...

journal_title：Clinical rheumatology

authors： Kobak S,Kobak AC,Kabasakal Y,Doganavsargil E

更新日期：2007-02-01 00:00:00

abstract：:2'5'-Oligoadenylate synthetase (OAS) was shown to be related to systemic lupus erythematosus (SLE) 20 years ago, and was rediscovered to be involved in type I interferon pathway in SLE by several microarray gene expression studies recently. The goal of this study was to investigate OAS isoform expressions in lupus pat...

journal_title：Clinical rheumatology

authors： Ye S,Guo Q,Tang JP,Yang CD,Shen N,Chen SL

更新日期：2007-02-01 00:00:00

abstract：UNLABELLED:There is a paucity of data on the impact of chronic rheumatic diseases on functional disability and overall health-related quality of life (HRQOL) in Africans. MATERIALS AND METHODS:We compared Black South Africans (BSA) with rheumatoid arthritis (RA) (n=50) and systemic lupus erythematosus (SLE) (n=50) to ...

journal_title：Clinical rheumatology

authors： Benitha R,Tikly M

更新日期：2007-01-01 00:00:00

abstract：:This study aims to characterize the clinical features of a cohort of patients diagnosed with systemic sclerosis (SSc) after the age of 75 and compare them to a group diagnosed at a younger age. We record the review of 769 patients diagnosed with SSc over the past 16 years. Utilizing a nested case-control model, we com...

journal_title：Clinical rheumatology

authors： Derk CT,Artlett CM,Jimenez SA

更新日期：2006-11-01 00:00:00

abstract：:Behcet's disease (BD) is a systemic vasculitis characterized by genital and oral ulcers, uveitis, and other organs' involvement. Left ventricular (LV) diastolic dysfunction has been documented in BD. However, conventional echocardiographic techniques have serious limitations like its dependence on preload, afterload a...

journal_title：Clinical rheumatology

authors： Baris N,Okan T,Gurler O,Akdeniz B,Turker S,Ilknur T,Akkoc N,Goldeli O

更新日期：2006-11-01 00:00:00

abstract：:Idiopathic paroxysmal rhabdomyolysis indicating a classical triad of symptoms consisting of muscle pain, weakness, and discolored urine is known as "Meyer-Betz syndrome". It may result in acute renal failure due to precipitation of the myoglobin casts in the tubuli or to the direct toxic effects of myoglobin to the tu...

journal_title：Clinical rheumatology

authors： Kasap B,Soylu A,Türkmen M,Kavukcu S

更新日期：2006-11-01 00:00:00

abstract：:We investigated whether headache and family history of headache are risk factors for complex regional pain syndrome (CRPS) or not. Twenty-three CRPS patients and 69 healthy persons were interviewed whether or not they suffered from headache and had first-degree family history of headache. A headache sufferer was defin...

journal_title：Clinical rheumatology

authors： Toda K,Muneshige H,Maruishi M,Kimura H,Asou T

更新日期：2006-09-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is a complex autoimmune disorder that affects various organs and systems. Increased apoptosis, together with defects in the uptake of apoptotic bodies, are thought to have a pathogenic role in SLE. By detection of chromatin condensation, 30% of apoptosis was detected in peripheral bl...

journal_title：Clinical rheumatology

authors： Pitidhammabhorn D,Kantachuvesiri S,Totemchokchyakarn K,Kitiyanant Y,Ubol S

更新日期：2006-09-01 00:00:00

abstract：:Adult-onset Still's disease (AOSD) has often been regarded as the adult spectrum of systemic juvenile idiopathic arthritis (sJIA). The present study aims to compare the clinical and laboratory features, the disease course and the response to treatment in patients having AOSD with those having sJIA. Retrospective revie...

journal_title：Clinical rheumatology

authors： Pay S,Türkçapar N,Kalyoncu M,Simşek I,Beyan E,Ertenli I,Oztürk MA,Düzgün N,Erdem H,Ozbalkan Z,Kiraz S,Kinikli G,Besbas N,Dinç A,Ateş A,Olmez U,Calgüneri M,Aydintuğ OT,Bakkaloğlu A,Turan M,Turgay M,Karaaslan Y,

更新日期：2006-09-01 00:00:00

abstract：:We report a 54 year old female whose successful treatment of cerebral lupus with rituximab was complicated by the development of streptococcus intermedius, on valves damaged by Libman-Sacks endocarditis more than 20 years previously. ...

journal_title：Clinical rheumatology

authors： Armstrong D,Wright S,McVeigh C,Finch M

更新日期：2006-07-01 00:00:00

abstract：:The lactogenic hormone prolactin is produced in part by cells of the immune system and serves as an upregulator of immune function. Hyperprolactinemia is common in patients with systemic lupus erythematosus (SLE), raising the possibility that the hormone contributes to the excessive immune response in the disease. The...

journal_title：Clinical rheumatology

authors： Li M,Keiser HD,Peeva E

更新日期：2006-07-01 00:00:00

abstract：:Ochronotic spondyloarthropathy is a rare metabolic disease with the musculoskeletal manifestations of alkaptonuria. Ochronotic arthropathy patients may have spinal abnormalities similar to ankylosing spondylitis (AS). The proof of sacroiliac involvement or bamboo spine appearance is not sufficient either for diagnosis...

journal_title：Clinical rheumatology

authors： Balaban B,Taskaynatan M,Yasar E,Tan K,Kalyon T

更新日期：2006-07-01 00:00:00

abstract：OBJECTIVE:Familial Mediterranean fever (FMF) is a hereditary disease characterized by recurrent attacks of fever with peritonitis, arthritis, pleuritis or erysipelas-like rash. It is unclear what effects of FMF itself on endocrine system and hormones are. None of the FMF patients without amyloidosis have been reported ...

journal_title：Clinical rheumatology

authors： Sav T,Ozbakir O,Kelestimur F,Gursoy S,Baskol M,Kula M,Dundar M

更新日期：2006-07-01 00:00:00